Myocardial Iron Quantification
| Purpose | Myocardial iron quantification |
| Tag(s) | |
| Panel | Cardiac |
| Define-AI ID | 19040028 |
| Originator | Akos Varga-Szemes |
| Lead | Akos Varga-Szemes |
| Panel Chair | Carlo De Cecco |
| Panel Reviewers | Cardiac Panel |
| License | |
| Status | |
| RadElement Set | RDES135 |
Clinical Implementation
Value Proposition
T2* cardiovascular magnetic resonance (CMR) is an effective and robust non-invasive tool for tissue iron measurement. An algorithm that provides myocardial T2* values based on the 17-segment model would improve clinical workflow.
Narrative(s)
Patients with siderosis with suspected myocardial involvement undergo T2* mapping of the heart. Normally, T2* maps are analysed by placing ROIs in the myocardium. The algorithm should be able to fully automate the segmentation and T2 fitting process, without any user input.
Workflow Description
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Patient undergoes T2* mapping of the heart, that is usually done in 3 short axis slices
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Algorithm receives inputs:
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Imaging dataset
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Algorithm executes:
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Automatically segments LV myocardium based on the 17-segment model
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Calculates T2* using the known fitting algorithm
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Displays segmental T2* on a bulls-eye diagram and indicates pathologic values (<20ms)
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Considerations for Dataset Development
| Age | Varied |
| Sex at Birth | Male, Female |
| Blood disorders | varied |
| BMI | varied |
| Heart Rate | varied |
| Scanner Vendor | Varied |
| Field Strength | [0.2 T, 7T] |
| Pulse sequence type | {spin echo sequences, inversion recovery sequences, gradient echo sequences, diffusion weighted sequences, saturation recovery sequences, echo-planar pulse sequences, spiral pulse sequences} |
| Pulse sequence scheme | varied |
Technical Specifications
Inputs
DICOM Study
| Procedure | CMR |
| Views | |
| Data Type | DICOM |
| Modality | MR |
| Body Region | Chest |
| Anatomic Focus | Heart |
Primary Outputs
T2* Value
| RadElement ID | RDE889 |
| Definition | the inherent decay of transverse magnetisation caused by a combination of spin-spin relaxation and magnetic field inhomogeneity |
| Data Type | Numeric |
| Value Set | N/A |
| Units | ms |
Secondary Outputs
Segmental T2*
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RadElement ID
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RDE889
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Definition
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display segmental T2* values on a bulls-eye diagram and indicate pathlogic values
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Data Type
| N/A |
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Value Set
| N/A |
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Units
| N/A |