Hip Osteolysis

Purpose	Measure osteolysis in the hip
Tag(s)	#THA
Panel	Musculoskeletal
Define-AI ID	18050003
Originator	Munib Sana
Panel Chair	Jay Patti
Panel Reviewers	Musculoskeletal Panel
License	Creative Commons 4.0
Status	Public Commenting

Clinical Implementation

Value Proposition

There are roughly 400,000 total hip arthroplasties (THAs) performed annually. Every patient has annual follow-up exams, which can add up to about 100 reads per day for an MSK radiologist who works with arthroplasty surgeons. Aseptic loosening and adverse local tissue reaction (ALTR) complicate a significant number of THAs and necessitate revision arthroplasty. These are indolent processes that, if not detected early, can lead to osteolysis or extensive tissue necrosis. Findings are not readily apparent on x-ray and require comparison with multiple prior exams to see progression of abnormality over time. AI meeting this use case would help to reduce false negative rate, patient risk, and medical legal risk for the radiologists. High-risk patients could be screened for elevated serum cobalt levels and sent to MRI for further evaluation. Delay in diagnosis could delay treatment for years.

Narrative(s)

A 65-year-old patient presents for annual follow-up THA x-ray. An algorithm evaluates the image and may also compare this exam with multiple prior exams. The algorithm detects if osteolysis is present to assist the radiologists in the interpretation of the patient’s THA status.

Workflow Description

The current image and accessible, prior hip x-rays are analyzed by the engine. Between the current image and images at least five years old or initial post-op film (if THA was performed less than five years ago), the engine can detect osteolysis. The images are returned to the radiologist at the time of interpretation.

Considerations for Dataset Development

Procedures(s): X-ray, hip

View(s): {AP, frog-leg lateral, cross-table lateral}

 

Sex at Birth: {Male, female}

 

Osteolysis Location: {Gruen zone 1, Gruen zone 7, Gruen zone 8, Gruen zone 14}

 

Interval Between Imaging (years): [0,20]

 

Comorbidities: {Calcar resorption, osteoporosis, subsidence, lucency}

Technical Specifications

Inputs

DICOM Study

Procedure	XRAY, Hip
Views	AP, frog-leg lateral, cross-table lateral
Data Type	DICOM
Modality	XRAY
Body Region	Pelvis
Anatomic Focus	Hip

Primary Outputs

Hip Osteolysis

RadElement ID	RDE212
Definition	Detect osteolysis, if present
Data Type	Categorical
Value Set	0–Unknown 0–Present 1–Absent
Units	N/A

Secondary Outputs

Total Hip Arthoplasty Status

RadElement ID	RDE213
Definition	Status of the total hip arthroplasty
Data Type	Categorical
Value Set	0–Unknown 1–Normal 2–Abnormal
Units	N/A

Related Datasets

No known related public datasets at this time, please us alert us if you know of any.