February 17, 2020

NRG Oncology Trial Shows Hippocampal Avoidance During Whole-Brain Radiotherapy for Brain Metastases Reduces Risks of Cognitive Toxicity and Neurologic Symptoms

Results from the NRG Oncology clinical study NRG-CC001 concluded that lowering radiotherapy dose to hippocampal stem cells improves cognitive and patient-reported outcomes for patients with brain metastases. These findings were presented at Plenary Sessions at the 2018 Society for Neuro-Oncology (SNO) and the 2019 American Academy of Neurology (AAN) Annual Meetings and are now published in the Journal of Clinical Oncology.

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