
Pisano served as principal investigator for the American College of Radiology Imaging Network (ACRIN) Digital Mammographic Imaging Screening Trial (DMIST). The landmark study showed that digital mammography was as accurate as film mammography in most women and detected more cancers than screen film in younger women, premenopausal and perimenopausal women, and women with dense breasts. Pisano is vice-chair of research and a staff radiologist at Beth Israel Deaconess Medical Center and is on the faculty at Harvard Medical School.