Mammograms Catch Few Cancers in Young Women: Study
Last Updated: 2010-05-03 18:45:10 -0400 (Reuters Health)
WASHINGTON (Reuters) - Mammograms detect few cancers in women under the age of 40 but cause expense and anxiety because women frequently get "false positives" that require follow-up to rule out cancer, researchers reported on Monday.
Mammograms did not detect any tumors among women under the age of 25, the researchers reported online May 3rd in the Journal of the National Cancer Institute.
The study of more than 117,000 U.S. women may reinforce controversial recommendations about the use of mammograms to screen for breast cancer among younger women.
Radiologist Dr. Bonnie Yankaskas of the University of North Carolina at Chapel Hill and colleagues examined the records of women who had their first mammograms between the ages of 18 to 39, starting in 1995.
During a year of follow-up, none of the women under age 25 had tumors. Among women aged 35 to 39, 12.7 per 1,000 got called back for second looks at suspicious lesions, but very few actually had tumors.
"In a theoretical population of 10,000 women aged 35 to 39 years, 1,266 women who are screened will receive further workup, with 16 cancers detected and 1,250 women receiving a false-positive result," Dr. Yankaskas and colleagues wrote.
"Harms need to be considered, including radiation exposure because such exposure is more harmful in young women, the anxiety associated with false-positive findings on the initial examination, and costs associated with additional imaging," they added.
About 29% of U.S. women aged 30 to 40 say they have had a mammogram.
Dr. Ned Calonge of the Colorado Department of Public Health and Environment said the findings suggest that women under 40 should not get mammograms unless they have symptoms of breast cancer.
Last November the U.S. Preventive Services Task Force said women in their 40s with an average risk for breast cancer did not need annual mammograms to screen for the disease.
The guidelines touched off a debate among oncologists.
Dr. Calonge, who is also chair of the task force, said most groups agree that women under 40 probably do not need mammograms to screen for cancer and Monday's study supports this approach.
http://jnci.oxfordjournals.org/cgi/content/abstract/djq090v1
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